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A drug which treats obesity by reducing the desire to eat has been launched.
But Medical chiefs warned people not to expect it to become widely available straight away as the cost-effectiveness of the pill needed to be assessed.

Rimonabant Acomplia is the first drug to target factors governing the body’s appetite, metabolism and energy use. Trials showed it can reduce weight by a tenth.

Experts have stated that acomplia could not replace healthy food and regular exercise.

In the UK and other countries, it is estimated that one in five men and a quarter of women are obese.

The Acomplia drug’s manufacturer, Sanofi Aventis, has argued the drug represents good value for money when set against the many billions of $$ per year cost of fighting obesity.

Other anti-obesity drugs are already available, but rimonabant is the only one to target the endocannabinoid system, which governs the body’s appetite.

In a series of trials involving more than 6,000 patients in the US and Europe, a quarter lost more than 10% of their initial body weight after a year. About half lost more than 5%.

Side effects in some patients included nausea, dizziness and anxiety.

Significant improvements in measures of glucose control, cholesterol and triglyceride blood fats were also seen.

Smoking

Rimonabant, sold under the brand name Acomplia, is currently licensed for the treatment of obese patients, or overweight patients with associated risk factors such as type 2 diabetes or poor cholesterol and triglyceride readings.

But there are also trial data suggesting that the drug can help people give up smoking by overcoming their cravings.

However at present it is only being marketed to tackle obesity.

Dr David Haslam, clinical director of the National Obesity Forum, said the drug offered a real opportunity to get to grips with the obesity crisis.

“Preventative measures aren’t enough on their own. It brings into focus the priority that should be given to treatment as well as prevention.

“The launch of rimonabant is important news for patients who are overweight, with type 2 diabetes, or low HDL cholesterol or high triglycerides.”

Acomplia Rimonabant: Weight Loss Includes Smoking Cessation

Rimonabant (also known as Zimulti, Acomplia or Slimona) is an anorectic anti obesity drug. It is a CB1 cannabinoid receptor antagonist. Rimonabant has been found to stop food craving enough to help people lose weight, and could also help curb other unhealthy urges, such as smoking. This is a non-controlled weightloss pill solution that in one study, helped people who were overweight drop an average of 20 pounds, and was found to be very useful for patients who suffer from obesity.

How does Rimonabant - Acomplia work?

Acomplia Rimonabant acts by selectively blocking CB1 receptors found in the brain and in peripheral organs important in glucose and lipid (or fat) metabolism, including adipose tissue, the liver, gastrointestinal tract and muscle1
Rimonabant acomplia switches off the same brain circuits that make people hungry when they smoke cannabis.  CB1 receptor blockade with Rimonabant acts to decrease the overactivity of the endocannabinoid system (EC system)2,3. The EC system is a recently characterised physiological system that includes receptors such as the CB1 receptor and it has been shown to play an important role in regulating body weight and in controlling energy balance, as well as glucose and lipid (or fat) metabolism.

Acomplia Tips:

Consult your doctor before using Acomplia. This will give you a chance to have your blood pressure and blood cholesterol level checked. When You decide on acomplia Your doctor may also help you craft an exercise routine that is least likely to aggravate any medical conditions or physical limitations you might have.

With Acomplia Keep your goals realistic. If you are an overweight, woman with a family history of obesity, it is unrealistic to expect the scale to ever read 110 pounds. Recent research has shown that even a 10 percent weight loss can significantly reduce your risk for heart disease, certain cancers, diabetes, and other health problems.

Before buying acomplia set short-term goals. If you have 50 or 100 pounds to lose, the mere thought of reaching your goal weight can be overwhelming. Instead, shoot for a series of 8- or 10-pound weight losses every month or so. Or aim to lose a dress size by your birthday a couple of months down the road. Then set another short-term fitness goal, such as losing an inch around your waist over the next month.

Drink up with acomplia.  Drink plenty of water before, during acomplia use and exersize, and after your exercise program, regardless of whether you are thirsty or perspiring.